Extensive physical disabilities have been demonstrated including diabetes , heart disease , stroke , excessive fat, , infection , cancer , joint and bone disease , and inflammation . The physical problems are extensive.
In spite of the extensive pathology, attempts to treating overeating of processed foods have not helped, and in some cases, have made diseases worse. The failure of weight-loss schemes is measured at 95% and above [25, 26]. Wieght-loss surgery patients exhibit slow weight regain [27, 28] and a tendency to develop alcoholism . Pharmaceuticals add to the distress with side effects such as weight regain , heart disease with fenfluramine and dexfenfluramine , suicide ideation with Rimonabant , memory loss and heightened anxiety from the most recent drugs Lorcaserine and Phentermine-topiramate , hypertension from Sibutramine , and bowel leakage from Orlistat .
What has worked is eliminating processed foods in favor of unprocessed foods. Cravings and the urge to overeat gradually diminish. People are able to watch many of the above-described diseases fade away.
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35. Hollywood, A. and J. Ogden, Taking Orlistat: Predicting Weight Loss over 6 Months. J Obes, 2011. 2011: p. 806896.